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BioProject ID : KAP230674

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Project title : A study on overcoming visual senescence by applying anti-aging technology to senescent cells

Submitter

**Submitter**
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Name	CHUNG HYEWON
Organization	Konkuk University school of Medicine
Department	Department of Ophthalmology

Date

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Registration Date	2023-11-30

Project Design

**Project Design**
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NTIS Number	1711200893
Project Title	A study on overcoming visual senescence by applying anti-aging technology to senescent cells
Relevance	medical
Description	Address heterogeneous composition in senescent RPE cells and identify what subpopulation might be changed by senolytic molecule tha Mito-K2 induction.
Project Data Type *	Whole Genome sequencing
Sample Scope *	Monoisolate

Hierarchy

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Umbrella Project	-

Publications

**Publications**
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PubMed ID	37664981
DOI	https://doi.org/10.1021/jacs.3c06898

Sample Group

BioSample Accession ID	Project Title	Sample Type	Registration Date
KASG231123	A study on overcoming visual senescence by applying anti-aging technology to senescent cells	Model organism or animal sample	2023-11-30
KASG231129	Single-cell transcriptomes of the mouse retinal pigment epithelium response to senescence induced by Alu-RNA and changes observed after Mito-K2 treatment.	Model organism or animal sample	2023-11-30

Submitter’s other BioProjects

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BioProject Accession ID	Project Title	Sample Scope	Project Data Type	Registration Date
KAP230732	In vivo efficacy of NRL knockdown with cell-penetrating siRNA in retinal degeneration	Monoisolate	Whole Genome sequencing	2024-02-14
KAP230672	in vivo effect of NRL Gene Silencing	Single cell	Transcriptome or Gene Expression	2023-11-30
KAP230679	Study of regenerative mechanisms of retinal pigment epithelium via expression of early differentiation-related transcription factors in retina	Monoisolate	Whole Genome sequencing	2023-12-07
KAP230673	A study on overcoming visual senescence by applying anti-aging technology to senescent cells	Monoisolate	Whole Genome sequencing	2023-11-30
KAP230671	in vivo effect of RORb Gene Silencing	Single cell	Transcriptome or Gene Expression	2023-11-30
KAP230545	Study of regenerative mechanisms of retinal pigment epithelium via expression of early differentiation-related transcription factors in retina	Monoisolate	Transcriptome or Gene Expression	2023-02-10
KAP220518	Development of macular degeneration treatment technology by inducing direct conversion of retinal cells in vivo	Single cell	Transcriptome or Gene Expression	2022-12-15
KAP220487	Development of vision rejuvenation technologies by controlling senescent cell fates	Monoisolate	Whole Genome sequencing	2022-10-19
KAP230674	A study on overcoming visual senescence by applying anti-aging technology to senescent cells	Monoisolate	Whole Genome sequencing	2023-11-30
KAP230678	Study of regenerative mechanisms of retinal pigment epithelium via expression of early differentiation-related transcription factors in retina	Monoisolate	Whole Genome sequencing	2023-12-07

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