BioProject ID : KAP220518
|Project title : Development of macular degeneration treatment technology by inducing direct conversion of retinal cells in vivo
Name | CHUNG HYEWON |
---|---|
Organization | Konkuk University school of Medicine |
Department | Department of Ophthalmology |
Registration Date | 2022-12-15 |
---|
NTIS Number | 1711159237 |
---|---|
Project Title | Development of macular degeneration treatment technology by inducing direct conversion of retinal cells in vivo |
Relevance | medical |
Description | The final goal of this study is to develop a new concept treatment for age-related macular degeneration (AMD), which causes intractable blindness, through the development of in vivo retinal cell conversion technology. By knocking down NRL and RORβ, which are key transcription factors for photoreceptor (PR) rod cell differentiation, which are concentrated in the central periphery of the macula, converting rods into cone-like cells (iCPR), improving central vision and preventing rod cell death. It is intended to establish a direct cross-differentiation technology in vivo that can mitigate. |
Project Data Type * | Transcriptome or Gene Expression |
Sample Scope * | Single cell |
Umbrella Project | - |
---|
PubMed ID | |
---|---|
DOI |
BioSample Accession ID |
Project Title
|
Sample Type
|
Registration Date
|
---|---|---|---|
KASG220911 | Single cell transcriptome of siRORbeta-treated mouse retina. | Model organism or animal sample | 2022-12-18 |
고객님께서 요청하신 내용을 처리중입니다.
잠시만 기다려주세요.