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BioProject ID : KAP220132

Project title : microRNAs profiling of ADPKD mouse model for novel therapeutic targets

Submitter

**Submitter**
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Name	Park JongHoon
Organization	SOOKMYUNG WOMEN'S UNIVERSITY
Department	DIVISION OF BIOLOGICAL SCIENCES

Date

**Date**
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Registration Date	2022-01-17

Project Design

**Project Design**
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NTIS Number	1711031849
Project Title	microRNAs profiling of ADPKD mouse model for novel therapeutic targets
Relevance	model_organism
Description	The purpose of this project is identification of microRNAs involved in cystogenesis of autosomal dominant polycystic kidney disease (ADPKD) and target genes of these miRNAs via next generation sequencing and bioinformatic analysis. We investigated miRNA-mediated regulatory systems and networks that play an important role during cystogenesis through integrative analysis of miRNA- and RNA-seq using two ADPKD mouse models (conditional Pkd1- or Pkd2-deficient mice).
Project Data Type *	Transcriptome or Gene Expression
Sample Scope *	Monoisolate

Hierarchy

**Hierarchy**
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Umbrella Project	KAU200000

Publications

**Publications**
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PubMed ID
DOI

Sample Group

BioSample Accession ID	Project Title	Sample Type	Registration Date
KASG220171	PKD mouse kidney tissue and normal mouse kidney tissue	Model organism or animal sample	2022-01-17

Submitter’s other BioProjects

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BioProject Accession ID	Project Title	Sample Scope	Project Data Type	Registration Date
KAP220356	Investigation of association between gut microbiota and type 2 diabetes	Multiisolate	Whole Genome sequencing,Transcriptome or Gene Expression	2022-07-05
KAP220279	Generation of epigenome/transcriptome data and biomarker discovery of diffuse type gastric cancer	Multiisolate	Transcriptome or Gene Expression	2022-04-28
KAP220130	Development of novel microbiome-driven therapies based on the meta-omics analysis	Monoisolate	Transcriptome or Gene Expression	2022-01-17
KAP220133	Development of YOBMT (Your Own Blended Microbiome Therapeutics) in metabolic/immune disorders	Environment	Metagenome	2022-01-17
KAP220131	Drug target validation using transcriptome and the CRISPR/Cas9 systems	Synthetic	Epigenomics,Transcriptome or Gene Expression	2022-01-17
KAP220358	Development of a pathogen control platform based on multiple interactions among enteric pathogens, symbiotic microbiome and host: from the perspectives of symbiotic microbiome	Multiisolate	Metagenome	2022-07-05
KAP220132	microRNAs profiling of ADPKD mouse model for novel therapeutic targets	Monoisolate	Transcriptome or Gene Expression	2022-01-17
KAP220357	Genomics-based drug response prediction technologies in refractory cancers	Multiisolate	Transcriptome or Gene Expression	2022-07-05
KAP220361	Epigenome/transcriptome-based immune profiling for the prediction of cancer immunotherapy against lung cancer	Multiisolate	Whole Genome sequencing	2022-07-05
KAP220134	Proteogenomics analysis and mechanism study to develop precision medicine for treatment-resistant pancreatic cancer	Multiisolate	Phenotype/Genotype,Transcriptome or Gene Expression	2022-01-17
KAP220359	Development of a prediction system for precision treatment of colorectal cancer by pharmacotranscriptome analysis of organoids	Multiisolate	Transcriptome or Gene Expression	2022-07-05
KAP220135	Proteogenomic analyses for developments of gastric cancer companion diagnostics and for targeted therapeutics candidates for refractory cancers	Multiisolate	Phenotype/Genotype,Transcriptome or Gene Expression	2022-01-17
KAP220362	Establishment of integrated RNome data and novel mechanisms for chronic liver disease	Monoisolate	Transcriptome or Gene Expression	2022-07-05
KAP220366	Discovery and functional study of target genes of natural and climacteric mouse skin aging model	Monoisolate	Transcriptome or Gene Expression	2022-07-05
KAP220136	Proteogenomics analysis and mechanism study to develop precision medicine for treatment-resistant pancreatic cancer	Multiisolate	Phenotype/Genotype,Transcriptome or Gene Expression	2022-01-17
KAP220364	Development of genomics-based therapeutic strategy targeting natural and climacteric aging in human skin	Multiisolate	Transcriptome or Gene Expression	2022-07-05
KAP220369	Development of targeting proteogenomic technology for refractory cancer treatment	Multiisolate	Whole Genome sequencing	2022-07-05
KAP220367	driver pathway prediction with disease related genome annotation	Multiisolate	Whole Genome sequencing	2022-07-05
KAP220363	Identification of diagnostic markers for chronic liver diseases by analyzing changes in chromatin remodeling patterns	Multiisolate	Whole Genome sequencing	2022-07-05
KAP220127	Development of a pathogen control platform based on multiple interactions among enteric pathogens, symbiotic microbiome and host: from the perspectives of enteric pathogens	Environment	Metagenome	2022-01-17
KAP220129	Disease research using fission yeast gene deletion library and next-generation sequencing (NGS) method	Monoisolate	Whole Genome sequencing	2022-01-17
KAP220128	Genome based Personal Medicine for Korean Rare Developmental Disease	Multiisolate	Exome	2022-01-17
KAP220365	Drug target identification using yeast deletion library	Multiisolate	Whole Genome sequencing,Epigenomics,Transcriptome or Gene Expression	2022-07-05
KAP220368	Development of bioinformatics platform of microbial community analysis for Korean patients with metabolic/immune disorders	Multiisolate	Metagenome	2022-07-05
KAP220360	Development of a prediction system for personalized treatment for colorectal cancer by pharmacoepigenomic analysis of organoids	Multiisolate	Whole Genome sequencing,Epigenomics	2022-07-05

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Summary 내용시작

Submitter

Date

Project Design

Hierarchy

Publications

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Sample Group

Submitter’s other BioProjects