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BioProject ID : KAP220196

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Project title : Breast cancer prognosis predictive gene selection and expression analysis

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Name Han Won Shik
Organization Seoul National University Hospital
Department Seoul National University Hospital

Date

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Registration Date 2022-04-12

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Project Title Breast cancer prognosis predictive gene selection and expression analysis
Relevance medical
Description 1) Using 40 estrogen receptor-related genes and 40 cell proliferation-related genes selected through NGS analysis of 120 Korean breast cancers in previous research, stabilization of target gene RNA sequencing technology and protocol development in 10-20 pilot samples 2) 200 patients who underwent OncotypeDX at two institutions, breast cancer FFPE tissue after surgery was secured and target gene RNA sequencing was performed. Based on this, development and validation of a prognostic scoring system 3) Securing breast cancer FFPE tissue after surgery for 800 patients who were followed for a long time without receiving chemotherapy for estrogen receptor-positive breast cancer in the past at two institutions. Reconfirmation of accuracy by applying target gene RNA sequencing and prognostic prediction model 4) Commercialization of the developed Korean prognostic tool
Project Data Type * Transcriptome or Gene Expression
Sample Scope * Multiisolate

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Sample Group

BioSample
Accession ID
Project Title
Sample Type
Registration Date
KASG220276 Estrogen-positive breast cancer prognostic predictive gene expression level analysis Human sample 2022-04-12
KASG220272 Estrogen-positive breast cancer prognostic predictive gene expression level analysis Human sample 2022-04-12

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