 Acute myeloid leukemia subtype M4 with eosinophilia is associated with a chromosome 16 inversion that creates a fusion gene CBFB-MYH11.     ///    We have previously shown that CBFB-MYH11 is necessary but not sufficient for leukemogenesis.     ///    "Here, we report the identification of genes that specifically cooperate with CBFB-MYH11 in leukemogenesis. "