Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function.    ///    "This observation, combined with functional assays, suggests that a stem-cell compartment drives PTPRK-RSPO3 colorectal tumour growth and indicates that the therapeutic targeting of stem-cell properties within tumours may be a clinically relevant approach for the treatment of colorectal tumours. "    ///    Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function.. 