Ewing-like sarcoma with CIC-DUX4 gene fusion in a patient with neurofibromatosis type 1.     ///     Sarcoma with CIC-DUX4 gene fusion is emerging as the most prevalent subset of Ewing-like undifferentiated small round cell sarcomas with around 50 cases published.     ///    This is the first case of sarcoma with CIC-DUX4 gene fusion reported in a patient with NF1.     ///    Whether this association is coincidental or CIC-DUX4 sarcomas could be related to NF1 remains to be clarified.     ///    "Study of alternative molecular alterations in EWSR1-negative undifferentiated small round cell sarcomas is clinically relevant, since CIC-DUX4 sarcomas seem to be a very aggressive subset with poor response to the presently used therapeutic regimens. "    ///    We report hereby the case of a 40-year-old male who presented a CIC-DUX4 sarcoma in deep soft tissues in his thigh.     ///    "The CIC-DUX4 sarcoma was treated with surgical resection, radiation and chemotherapy, but lung and brain metastases developed and the patient died from the disease 14 months after diagnosis. "