 MDM2/CDK4 gene amplification has been shown to be sensitive and specific for the diagnosis of well-differentiated lipoma-like liposarcoma (WD-LLLPS).     ///    "The incidence of MDM2/CDK4 amplification was reassuringly low (5%) in this cohort of LN, despite their large and/or deep-seated nature. "    ///    Two (3%) cases showed dual MDM2/CDK4 amplification and 2 (3%) showed MDM2 amplification alone.     ///    Mdm2/Cdk4 amplification in large and/or deep-seated lipomatous neoplasms without overtly atypical morphological features..     ///    "The clinical, radiological and pathological features of all cases with CDK4/MDM2 amplification were reviewed. "    ///    To assess the incidence of MDM2/CDK4 amplification in large and/or deep seated LN without overtly atypical morphological features and to examine the clinicopathological features of cases showing these alterations. 