In order to test the hypothesis that delocalization of PML from PODs is necessary for APL, we investigated the interaction of the t(5;17) APL fusion protein NPM-RAR with PML.     ///    The NPM-RAR fusion protein associated with the t(5;17) variant of APL does not interact with PML..     ///    These studies suggest that NPM-RAR does not interact with PML..     ///    "NPM-RAR does not alter the localization of PML in transfected HeLa cells, and does not associate with PML in vitro. "    ///    NPM-RAR localizes diffusely throughout the nucleoplasm. 