ELP 12 was found to be more selective for SSAO/VAP-1.     ///    "These structural data reveal that the entrance and the first part of the SSAO/VAP-1 channel may be considered as a new target area, or a ""secondary binding site"", for modulators of human SSAO/VAP-1 activity. "    ///    "The aim of this study was to evaluate the effect of some synthetic polyamines as inhibitors of two new potential targets, human semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1) and monoamine oxidases B (MAO B), enzymes involved in various multi-factorial diseases such as Alzheimer's disease. "    ///    "These results indicate ELP 12 and Bis-Bza-Diado as new ""skeletons"" for the development of novel SSAO/VAP-1 and MAO B inhibitors.. "    ///    "Combining kinetic and structural approaches, the binding mode of ELP 12 to SSAO/VAP-1 was investigated. "