Up-regulation of both genes emerged only in the presence of NUP98/HOXA13 gene fusion.     ///    Blast crisis Ph+ chronic myeloid leukemia with NUP98/HOXA13 up-regulating MSI2..     ///    "To the best of our knowledge, this is the first molecular characterization of NUP98/HOXA13 fusion in blast crisis of Ph?+?CML. "    ///    To determine the mechanisms underlying MSI2 over-expression in our patient we performed Chromatin Immunoprecipitation and found that NUP98/HOXA13 fusion protein deregulates MSI2 gene by binding its promoter. 