 MN1-TEL is the product of the recurrent t(12;22)(p12;q11) associated with human myeloid malignancies.     ///    "MN1-TEL, the product of the t(12;22) in human myeloid leukemia, immortalizes murine myeloid cells and causes myeloid malignancy in mice.. "    ///    "MN1-TEL functions as an activated transcription factor, exhibiting weak transforming activity in NIH3T3 fibroblasts that depends on the presence of a functional TEL DNA-binding domain, the N-terminal transactivating sequences of MN1 and C-terminal sequences of MN1. "    ///    "We infer that MN1-TEL is a hematopoietic oncogene that stimulates the growth of hematopoietic cells, but depends on secondary mutations to cause leukemia in mice.. "    ///    We determined the transforming activity of MN1-TEL in mouse bone marrow (BM) by using retroviral transfer. 