ADF/cofilin proteins translocate to mitochondria during apoptosis but are not generally required for cell death signaling..     ///    "Thus, we conclude that ADF/cofilin activity is not generally required for induction or progression of apoptosis in mammalian cells. "    ///     Non-muscle cofilin (n-cofilin) is a member of the ADF/cofilin family of actin depolymerizing proteins.     ///    "To elucidate the general importance of ADF/cofilin activity for apoptosis, we exposed mouse embryonic fibroblasts deficient for n-cofilin, ADF (actin depolymerizing factor), or all ADF/cofilin isoforms to well-characterized apoptosis inducers. "