U19/Eaf2 interacts with ELL, a fusion partner of MLL in the (11;19) (q23;p13.1) translocation in acute myeloid leukemia.     ///    Transfection and colony formation were used to assay for apoptosis and growth suppression of various U19/Eaf2 mutants.     ///     U19/Eaf2 is an androgen-response gene and its downregulation is frequently observed in advanced human prostate cancer.     ///    These observations argue that the interaction with ELL is essential for the induction of apoptosis and growth suppression by U19/Eaf2..     ///    The region of U19/Eaf2 essential for apoptosis and growth suppression was mapped to amino acids 68-113.     ///    U19/Eaf2 overexpression induces apoptosis and suppresses xenograft tumor growth.     ///    Co-expression of U19/Eaf2 and ELL in 293 cells lead to significant increase in cell death and growth suppression.     ///    Apoptosis induction and growth suppression by U19/Eaf2 is mediated through its ELL-binding domain..     ///    Co-immunoprecipitation was performed to test the interaction between the U19/Eaf2 constructs and ELL. 