Our findings indicate that the essential role of EGF-CFC genes and Nodal signalling in left-right axis formation is conserved from fish to humans.     ///    "The EGF-CFC genes, mouse Cfc1 (encoding the Cryptic protein. "    ///    Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects..     ///    "EGF-CFC proteins act as co-factors for Nodal-related signals, which have also been implicated in L-R axis development. "