The median time of FIP1L1-PDGFR alpha fusion gene becoming negative was 4 (1.5 - 8) months.     ///    "Eight MPN patients with eosinophilia and positive FIP1L1-PDGFR alpha gene and one CEL, NOS were treated with 100 mg or 400 mg/d imatinib orally. "    ///    Imatinib in treatment of MPN with eosinophilia and positive FIP1L1-PDGFR alpha gene patients can induce high hematologic and molecular remission. 