We confirmed the SS18-SSX1 translocation in all cell lines and identified a consistent splicing variant.     ///    We confirmed the presence of the SS18-SSX1 translocation in our cell lines and its importance in the survival of synovial sarcoma.     ///    SS18-SSX1 knockdown was achieved using a shRNA system.    ///    We (1) established and characterized three novel synovial sarcoma cell lines and asked (2) whether inhibition of SS18-SSX1 decreases cell viability in these cell lines.     ///    We achieved successful knockdown of SS18-SSX1 and with this saw a significant reduction in cell viability.     ///    and (3) whether reduction in viability after SS18-SSX1 knockdown is caused by apoptosis.     ///    Loss of SS18-SSX1 inhibits viability and induces apoptosis in synovial sarcoma.. 