ETV6-NTRK3 is a common chromosomal rearrangement in radiation-associated thyroid cancer..     ///    "Moreover, ETV6-NTRK3 rearrangement can be directly induced in thyroid cells by ionizing radiation in vitro and, thus, may represent a novel mechanism of radiation-induced carcinogenesis.. "    ///    "The prevalence of ETV6-NTRK3 rearrangement in post-Chernobyl PTCs was associated with increasing (131) I dose, albeit at borderline significance (P?=?.126). "    ///    The authors report the occurrence of ETV6-NTRK3 rearrangements in thyroid cancer and demonstrate that this rearrangement is significantly more common in tumors associated with exposure to (131) I and has a borderline significant dose response.     ///    "In vitro exposure of human thyroid cells to 1 gray of (131) I and ?-radiation resulted in the formation of ETV6-NTRK3 rearrangement at a rate of 7.9????10(-6) cells and 3.0????10(-6) cells, respectively. "    ///    "The group of rearrangement-positive PTCs (ETV6-NTRK3, RET/PTC, PAX8-PPAR?) was associated with significantly higher dose response compared with the group of PTCs with point mutations (BRAF, RAS. "