RET/PTC rearrangements were found in 33% of FHCAs and in 38% of FHCCs.     ///    "In an attempt to clarify this issue, we analysed a series of H?rthle cell tumours for the presence of RET/PTC and PAX8/PPARG rearrangements and BRAF, HRAS and NRAS mutations. "    ///    RET/PTC rearrangement is prevalent in follicular H?rthle cell carcinomas..     ///    An FHCC with a solid/microfollicular growth pattern scored positive for both RET/PTC and PAX8/PPARG rearrangement.     ///    "Our study has shown a significant association between RET/PTC rearrangements and FHCCs with a solid growth pattern, thus raising the possibility of using tyrosine kinase inhibitors for the treatment of patients with FHCCs, which are often refractory to radioiodine treatment.. "    ///    All RET/PTC-positive FHCCs had a solid pattern of growth. 