 The FIP1L1-PDGFRA rearrangement results in constitutive activation of the tyrosine kinase PDGFRA.     ///    The presence of a dominant neoplastic clone with FIP1L1-PDGFRA rearrangement was suspected on the basis of sudden onset of peripheral and bone marrow eosinophilia and confirmed by fluorescence in situ hybridization and molecular diagnostic tests.     ///    Discovery of imatinib-responsive FIP1L1-PDGFRA mutation during refractory acute myeloid leukemia transformation of chronic myelomonocytic leukemia..     ///    "Herein, we present a case report of a patient in whom the FIP1L1-PDGFRA was discovered as he evolved from CMML to acute myeloid leukemia (AML). "    ///    Only a single report has described the identification of FIP1L1-PDGFRA in chronic myelomonocytic leukemia (CMML). 