We analysed, whether detection of SYT-SSX1/2 fusion transcripts, present as a consequence of a specific translocation [t(X;18)(p11.2;q11.2)] found in synovial sarcomas, are useful to confirm the diagnosis of synovial sarcoma.     ///    DNA sequencing of PCR products enabled the assignment of fusion transcripts to either the SYT-SSX1 or the SYT-SSX2 variant.     ///    These data provide further evidence that the RT-PCR amplification of SYT-SSX1/2 fusion transcripts permits the specific identification of synovial sarcomas.     ///    A nested RT-PCR protocol was established for the detection of SYT-SSX1/2 fusion transcripts.     ///    We detected SYT-SSX1/2 fusion transcripts in seven monophasic and three biphasic synovial sarcomas. 