NPM-ALK signals through glycogen synthase kinase 3? to promote oncogenesis..     ///    Phosphorylation of pS(9)-GSK3? by NPM-ALK was mediated by the PI3K/AKT signaling pathway.     ///    Our results demonstrate that NPM-ALK regulates the phosphorylation of S(9)-GSK3? by PI3K/AKT.     ///    "Using a mass spectrometry-based phosphoproteomic screen, we identified GSK3? as a signaling mediator of NPM-ALK. "    ///    These findings provide support for the role of GSK3? as a mediator of NPM-ALK oncogenesis..     ///    "Expression of NPM-ALK in 293T cells led to an increase of pS(9)-GSK3? (glycogen synthase kinase 3 beta) compared with kinase-defective K210R mutant NPM-ALK, but did not affect total GSK3? levels. "    ///    "NPM-ALK is a chimeric tyrosine kinase, which induces numerous signaling pathways that drive proliferation and abrogate apoptosis. "