Among the 17 cases with KIAA1549-BRAF fusion gene 15 (88.2%) were oligodendroglial neoplasms.     ///    " KIAA1549-BRAF fusion gene and isocitrate dehydrogenase (IDH) mutations are considered two mutually exclusive genetic events in pilocytic astrocytomas and diffuse gliomas, respectively. "    ///    There were KIAA1549-BRAF fusion gene in 17 out of 180 (9.4%) cases and BRAF(v600E)  in 2 out of 133 (1.5%) cases.     ///    "Our results suggest that in a small fraction of diffuse gliomas, KIAA1549-BRAF fusion gene and BRAF(v600E)  mutation may be responsible for deregulation of the Ras-RAF-ERK signaling pathway. "    ///    The KIAA1549-BRAF fusion gene was evaluated by reverse-transcription polymerase chain reaction (RT-PCR) and sequencing.     ///    We investigated the presence of the KIAA1549-BRAF fusion gene in conjunction with IDH mutations and 1p/19q loss in 185 adult diffuse gliomas.     ///    "In 11 of these 17 cases, both IDH mutations and the KIAA1549-BRAF fusion were present, as independent molecular events. "    ///    KIAA1549-BRAF fusions and IDH mutations can coexist in diffuse gliomas of adults..     ///    "Moreover, 6 of 17 cases showed co-presence of 1p/19q loss, IDH mutations and KIAA1549-BRAF fusion. "