While characterization of its role in non-mammalian species remains largely unexplored, the presence of GPR54 in GnRH neurons and the changes in its expression during pubertal development, reported recently in fish species, are suggestive of a conserved function of the KiSS-1/GPR54 system in the control of reproduction during evolution..     ///    "In sum, compelling experimental evidence, obtained in mammals, has recently defined the pivotal role of the KiSS-1/GPR54 system in the control of essential aspects of female reproduction, from puberty to ovulation. "