Interestingly, miR-1-1/miR-133a-2,?miR-1-2/miR-133a-1, and miR-206/miR-133b form clusters in three different chromosomal regions of the human genome - 20q13.33, 18q11.2 and 6p12.1, respectively.     ///    Here we review highlights of recent findings on the aberrant expression and functional significance of?the miR-1/miR-133a and miR-206/miR-133b clusters in human cancers.. 