In the present study, we determined the genomic breakpoint and characterized the chimeric transcript of the EWSR1-ETV4 fusion gene in two t(17;22) Ewing sarcomas.     ///    These observations suggest a mechanism of EWSR1-ETV4 gene fusion..     ///    The genomic breakpoint and chimeric transcripts in the EWSR1-ETV4/E1AF gene fusion in Ewing sarcoma..     ///    The discovery of this translocation suggested that there might be a novel EWSR1-ETV4 fusion gene. 