In addition, K-ras mutation was analyzed for patients without EML4-ALK fusion genes.     ///    There were 39 patients (34%) with the EML4-ALK fusion gene.     ///    The K-ras mutation rate for patients without EML4-ALK fusion gene was 6.5%.     ///    "Comparing patients with tumors harboring variant 1 with those harboring nonvariant 1 EML4-ALK fusion genes, there were no significant differences in clinical factors and survival outcome. "    ///    "For lung adenocarcinoma patients with wild-type EGFR, EML4-ALK translocation is associated with longer overall survival.. "    ///    EML4-ALK translocation predicts better outcome in lung adenocarcinoma patients with wild-type EGFR..     ///    "By multivariate analysis, patients who had better performance status (p < 0.001) and EML4-ALK translocation (p = 0.017) had longer overall survival. "    ///    "For lung adenocarcinoma patients with wild-type EGFR, EML4-ALK translocation is associated with longer overall survival.."    ///    Lung adenocarcinoma patients with malignant pleural effusions having wild-type EGFR and measurable target lesions were enrolled for EML4-ALK analysis by reverse transcription-polymerase chain reaction and direct sequencing.     ///    "To understand the impact of EML4-ALK on the prognosis of non-small cell lung cancer, we examined EML4-ALK fusion in lung adenocarcinoma from patients with wild-type EGFR and analyzed their clinical treatment outcomes. "    ///    "To understand the impact of EML4-ALK on the prognosis of non-small cell lung cancer, we examined EML4-ALK fusion in lung adenocarcinoma from patients with wild-type EGFR and analyzed their clinical treatment outcomes."    ///    "Demographic data, EML4-ALK status, and survival data were analyzed. "    ///    "Demographic data, EML4-ALK status, and survival data were analyzed."    ///    EML4-ALK fusion is mutually exclusive with epidermal growth factor receptor (EGFR) mutations.     ///    " The echinoderm microtubule-associated protein like 4-anaplastic lymphoma kinase (EML4-ALK) fusion represents a novel target in a subset of non-small cell lung cancer, especially adenocarcinoma. "    ///    "The echinoderm microtubule-associated protein like 4-anaplastic lymphoma kinase (EML4-ALK) fusion represents a novel target in a subset of non-small cell lung cancer, especially adenocarcinoma."