 We investigated the role of ETV6/ARG fusion gene by exposing the HT93A cell line to nilotinib.     ///    ETV6/ARG oncoprotein confers autonomous cell growth by enhancing c-Myc expression via signal transducer and activator of transcription 5 activation in the acute promyelocytic leukemia cell line HT93A..     ///    Our data suggest that ETV6/ARG oncoprotein is a potential target in the treatment of leukemia..     ///    "These findings suggest that the ETV6/ARG oncoprotein contributes to autonomous cell growth by compensating for the requirement of growth factor through activating STAT5 signaling, which leads to the up-regulation of c-Myc. "