 In order to investigate the leukemogenic potential of NUP98-PMX1 fusion gene in vivo.     ///    "NIH3T3 cells transfected with NUP98-PMX1 fusion gene grew faster, formed colonies in soft agar, and developed tumors in 10 inoculated nude mice. "    ///    "NUP98-PMX1 transgenic mice were generated, in which the fusion gene was driven by hCG promoter and expressed in myeloid cells at early stage of differentiation. "    ///    "Among 8 disordered NUP98-PMX1 transgenic mice, 4 developed myeloid leukemia-like phenotype, including 3 resembling human chronic myeloid leukemia. "    ///    Molecular cloning technology was used to construct NUP98-PMX1 transgenic plasmid.     ///    "The genotype and phenotype of the NUP98-PMX1 transgenic mice were analyzed by PCR, RT-PCR, peripheral blood count (PBC), bone marrow (BM) cells morphology and pathological examination. "    ///    NUP98-PMX1 has oncogenic activity and plays a crucial role in leukemogenesis..     ///    [Development of human myeloid leukemia-like phenotype in NUP98-PMX1 transgenic mice].. 