 To investigate the effects of AML1B and AML1/ETO fusion gene on the transcription activity of TSC1 and TSC2 promotor and to explore its role in leukemogenesis.     ///    AML1B and AML1/ETO can regulate the transcription of TSC genes..     ///    "AML1/ETO showed a significant transactivity to TSC1, but no transactivity to TSC2's. "    ///    [The effects of AML1B and AML1/ETO on the transactivation of TSC genes.]..     ///    "However, AML1/ETO antagonized the effect of AMLlB to TSC2 gene promoter. "    ///    "The luciferase reporter plasmids of TSCs gene promoter containing a AML1 binding site were constructed, and cotransfected into CV-1 cells with AML1B or AML1/ETO expression plasmids separately. "