In contrast, one of the two t(17;19)+ ALLs that lacked p15/p16 homozygous deletions showed probable hemizygous p15 hypermethylation.     ///    "Previously, a negative association was found between the t(1;19) and homozygous p16/p15 deletions. "    ///    "However, little is known about the potential association between p16/p15 gene alterations and specific genetic abnormalities implicated in leukemogenesis. "