Quantitative real-time RT-PCR demonstrated that the expression of the CPQ-PRKDC fusion transcript was significantly lower than that of wild-type PRKDC, corresponding to a low transcript allele fraction of this fusion, based on RNA-sequencing read counts.     ///    "In endometrial cancers, the CPQ-PRKDC fusion transcript may be a passenger aberration related to gene amplification. "    ///    Cell proliferation of the fusion-positive cell line was inhibited by knocking down the expression of wild-type PRKDC but not by blocking the CPQ-PRKDC fusion transcript expression.     ///    We detected only CPQ-PRKDC fusion transcript in three of 122 primary endometrial cancer tissues.     ///    "As targetable fusion candidates, we focused on three in-frame kinase fusion transcripts that retain a kinase domain (CPQ-PRKDC, CAPZA2-MET, and VGLL4-PRKG1). "