Erythroid progenitors of the patients with t(8;21) AML expressed AML1/ETO.     ///    " The functions of AML1 in hematopoietic differentiation are repressed by AML1-mutants including the AML1/ETO chimeric protein, which is seen in t(8;21) acute myeloid leukemia. "    ///    "It was upregulated by AML1 and downregulated by AML1/ETO in both erythroid and myeloid cells, and increased during erythroid cell differentiation. "    ///    "To investigate the effect of AML1/ETO in erythroid cells, we made a tetracycline-regulated AML1/ETO overexpression system in mouse erythroleukemic (MEL) cells. "    ///    Enforced AML1/ETO repressed the terminal erythroid differentiation. 