Values ??mean +1 SD at H19/IGF2: IG-DMR were assigned to borderline hypermethylated BWS cases and those ??mean -2 SD at KCNQ1OT1: TSS-DMR to hypomethylated BWS cases.     ///    "Comparison of methylation levels by methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) in borderline and control cases defined an interval of H19/IGF2:IG-DMR loss of methylation that was distinct between ""easy to diagnose"" and ""borderline"" cases, which were characterized by values ??mean -3 standard deviations (SDs) compared to controls. "