 TMPRSS2-ERG gene fusion was recently reported as the most common gene rearrangement in prostate cancer (PCA).     ///    The TMPRSS2-ERG gene fusion status was homogenous within the same cancer focus and 82% of fusion positive PCA were present in GS 6 or 7 vs.     ///    "We sought to characterize the incidence, pathological features and clinical parameters of TMPRSS2-ERG gene fusion in a cohort of 196 Canadian men treated by radical prostatectomy for localized PCA, and to investigate its potential as a biomarker in PCA. "    ///    Using break-apart FISH assay to indirectly assess the fusion of TMPRSS2-ERG.     ///    "If confirmed, this could have significant clinical impact in further stratifying patients with PCA should the TMPRSS2-ERG be confirmed as a prognostic biomarker.. "    ///    The higher association of TMPRSS2-ERG with Gleason score 6 and 7 should be further investigated. 