 To observe the effects of AML1-ETO fusion gene on the transcription activity of p21WAF1/CIP1 gene.     ///    "AML1-ETO exhibits more inhibition activity of p21WAF1/CIP1 gene promoter than AML1b and AMLla, results from recruiting transcription co-repression complex efficiently by ETO. "    ///    [Effects of AML1-ETO on transcription activity of p21WAF1/CIP1 gene promoter]..     ///    "The luciferase reporter plasmids of p21WAF1/CIP1 gene promoter were constructed, and co-transfected into CV-1 cells with AML1-ETO, AML1b and AML1a expression plasmids. "    ///    AML1-ETO exhibited a distinct inhibition activity of p21WAF1/CIP1 gene promoter with a sequence-specificity and dosage-dependent manner.     ///    And to explore the enhancement of leukemia pathogenesis of AML1-ETO.     ///    "Based on previous researches, the effects of exogenous AML1-ETO on p21WAF1/CIP1 gene promote may be dependent on the type of cell lines.. "