In these lipomas, HMGA2/LPP fusion transcripts are expressed, which encode for the three AT-hooks of HMGA2 followed by the two most carboxyl-terminal LIM domains (protein-protein interaction domains) of LPP.     ///    These results support the concept that the transactivation functions of the novel HMGA2/LPP transcription factor contribute to lipomagenesis..    ///    These results support the concept that the transactivation functions of the novel HMGA2/LPP transcription factor contribute to lipomagenesis..     ///    "We also show that HMGA2/LPP activates transcription from the BAT-1 element of the rhodopsin promoter, a HMGA1-binding element. "    ///    "Finally, in a number of lipomas, HMGA2/LPP and HMGA2 are coexpressed, and HMGA2 augments the transactivation functions of HMGA2/LPP. "    ///    "Here, we show that the HMGA2/LPP fusion protein retains the transactivation functions of the LPP LIM domains and thus functions as transcription factor. "    ///    "The HMGA2/LPP fusion protein activates transcription from the well-characterized PRDII element, which is a part of the IFN-beta enhancer and which is known to bind to HMGA2. "    ///    Transactivation functions of the tumor-specific HMGA2/LPP fusion protein are augmented by wild-type HMGA2.. 