We observed that both GFI1 variants maintain the same activity as transcriptional repressors but differ in their regulation by the AML1/ETO (RUNX1/RUNX1T1) fusion protein produced in AML patients with a t(8;21) translocation.     ///    "As a consequence, AML1/ETO does not colocalize with GFI1(36N) and is unable to inhibit its repressor activity. "    ///    AML1/ETO interacts and colocalizes with the more common GFI1(36S) form in the nucleus and inhibits its repressor activity. 