 The ETV6-RUNX1 fusion is the molecular consequence of the t(12;21)(p13;q22) seen in approximately 25% of children with acute lymphoblastic leukemia (ALL).     ///    This study identifies deletions of TBL1XR1 as a recurrent abnormality in ETV6-RUNX1 positive ALL.     ///    The complex genomic profile of ETV6-RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR1.. 