This identifies KLF6 as a novel mediator of t(8;21) target gene regulation, providing a new mechanism for RUNX1-ETO transcriptional control..     ///    " Fusion protein RUNX1-ETO (AML1-ETO, RUNX1-RUNX1T1) is expressed as the result of the 8q22;21q22 translocation [t(8;21)], which is one of the most common chromosomal abnormalities found in acute myeloid leukemia. "    ///    "Furthermore, KLF6 is specifically upregulated by RUNX1-ETO in human leukemia cells. "    ///    Mechanisms of RUNX1-ETO target gene upregulation remain less well understood.     ///    RUNX1-ETO is thought to promote leukemia development through the aberrant regulation of RUNX1 (AML1) target genes. 