Our findings provide new information on the heterogeneity of conventional cytogenetics in ETV6/ABL1 positive leukemias, and indicate the putative target cell in this AML is an immature precursor capable of terminally differentiating towards eosinophils..     ///    Clonal eosinophils are a morphologic hallmark of ETV6/ABL1 positive acute myeloid leukemia..     ///    Our objective was to study two new cases of ETV6/ABL1-positive acute myeloid leukemia (AML) and to focus on bone marrow morphology and on molecular cytogenetics of eosinophilic cells.     ///    "Accordingly, an ETV6/ABL1 fusion signal was detected on der(8) in patient #1, and on der(9) in patient #2. "    ///    ETV6/ABL1 chimeric proteins have been detected both in lymphoid and myeloid disorders. 