 The ETV6/ABL1 (TEL/ABL) fusion gene is a rare aberration in malignant disorders.     ///    "The course of the disease in the two pediatric patients is characterized by minimal residual disease monitoring, using quantification of both the ETV6/ABL1 transcript and immunoreceptor gene rearrangements. "    ///    "A thorough review of the literature and an analysis of all published data, including the three new cases, suggest poor prognosis of ETV6/ABL1-positive acute leukemias. "    ///    "Only 19 cases of ETV6/ABL1-positive hematological malignancy have been published, diagnosed with chronic myeloid leukemia, other types of chronic myeloproliferative neoplasm, acute myeloid leukemia or acute lymphoblastic leukemia (ALL). "    ///    Eosinophilia could not be confirmed as a hallmark of the ETV6/ABL1-positive disease.     ///    Acute leukemias with ETV6/ABL1 (TEL/ABL) fusion: poor prognosis and prenatal origin..     ///    "This study reports three new cases (aged 8 months, 5 years, and 33 years) of ALL with the ETV6/ABL1 fusion found by screening 392 newly diagnosed ALL patients (335 children and 57 adults). "    ///    "Studies of neonatal blood spots demonstrated that, in the child diagnosed at five years, the ETV6/ABL1 fusion initiating the ALL originated prenatally.. "