This showed an association with the well-established AMD risk loci ARMS2 (age-related maculopathy susceptibility 2)-HTRA1 (HtrA serine peptidase 1) (P =2.7 ?? 10(-72)), CFH (complement factor H) (P =2.3 ?? 10(-47)), C2 (complement component 2)-CFB (complement factor B) (P =5.2 ?? 10(-9)), C3 (complement component 3) (P =2.2 ?? 10(-3)) and CFI (P =3.6 ?? 10(-3)) and with more recently reported risk loci at VEGFA (P =1.2 ?? 10(-3)) and LIPC (hepatic lipase) (P =0.04). 