Based on this analysis it appears that the biopsy of two blastomeres from embryos with ?7 blastomeres on day 3 is a valid and successful approach for couples presenting for IVF-PGD for a chromosome rearrangement..     ///    IVF-PGD couples had either one or two blastomeres biopsied from all embryos with ?7 blastomeres on day 3 post oocyte collection. 