Since a recent report directly proved that two cases of PHE/ES-HE have SERPINE1-FOSB fusion gene by reverse transcription-polymerase chain reaction (RT-PCR), we examined whether the fusion gene is present or not in the present case by RT-PCR using fresh frozen surgical material.     ///    Sequencing of the PCR product revealed that this case has SERPINE1-FOSB fusion.     ///    Penile pseudomyogenic hemangioendothelioma/epithelioid sarcoma-like hemangioendothelioma with a novel pattern of SERPINE1-FOSB fusion detected by RT-PCR--report of a case..     ///    "Thus, this is the third case of PHE/ES-HE with SERPINE1-FOSB fusion proved by RT-PCR. "