The cells had high protein kinase (p210BCR-ABL) activity and carried two identified variants of an ABL-BCR message.     ///    "We conclude that the KBM-7 cell line will be of value for investigating molecular events underlying neoplastic transformation in CML, in particular for studying the effects of BCR-ABL and ABL-BCR on the proliferation of CML cells in the absence of normal BCR and c-ABL messages.. "