 Human SET encodes a nuclear phosphoprotein with a highly acidic carboxyl-terminus, forming a SET-CAN fusion gene in a patient with acute undifferentiated leukemia.     ///    "Even though SET is involved in chromatin remodeling and transcriptional activation, its precise role in hematopoietic cells and the contribution of SET-CAN to leukemogenesis remains unknown. "    ///    "We determined the effect of tetracycline-regulatable expression of SET, a deletion mutant of SET, and SET-CAN on the human promonocytic cell line U937T. "    ///    Effects of SET and SET-CAN on the differentiation of the human promonocytic cell line U937..     ///    "SET-CAN most likely inhibits growth by interfering with hCRM1, but it also partially blocks differentiation. "    ///    The expression of SET and SET-CAN inhibited proliferation of these cells. 