In this review, we detail the structural features, functions, and models used to study both RUNX1 and RUNX1-ETO in hematopoiesis over the past two decades..     ///    RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis..     ///    The RUNX1-ETO fusion protein is found in approximately 12% of all AML patients. 