Recent studies show that NUP98-HOXD13 (NHD13) fusion gene results in myelodysplastic syndrome and impairs lymphocyte differentiation in transgenic mice.     ///    A NUP98-HOXD13 leukemic fusion gene leads to impaired class switch recombination and antibody production..     ///    Further delineation of the NUP98-HOXD13 transgene may reveal novel pathways involved in CSR..     ///    "Taken together, our findings show that expression of NUP98-HOXD13 impairs CSR and reduces the antibody-mediated immune response, in addition to its role in leukemia. "