Identifying regions with a similar epigenetic make up in t(8;21) acute myeloid leukemia (AML) cells, another subtype of AMLs, revealed that these regions are occupied by the oncofusion protein AML1-ETO.     ///    "Together, our results suggest that oncofusion proteins localize to accessible regions and that chromatin accessibility together with p300 binding and histone acetylation characterize AML1-ETO and PML-RAR? binding sites.. "    ///    "Chromatin accessibility, p300, and histone acetylation define PML-RAR? and AML1-ETO binding sites in acute myeloid leukemia.. "