These translocations form PAX3-FKHR and PAX7-FKHR gene fusions, which encode chimeric transcription factors.     ///    "This review highlights recent advances in numerous areas of biomedical investigation that are providing new insights into the biology, molecular pathology, and translational science of ARMS: the identification of downstream targets of PAX3-FKHR and collaborating events in the process of tumorigenesis and metastasis. "