 We identified a novel fusion gene, FOXP1-PDGFRA, in a patient with myeloproliferative neoplasm (MPN) with eosinophilia, harboring the chromosome abnormality t(3;4)(p13;q12).     ///    A novel FOXP1-PDGFRA fusion gene in myeloproliferative neoplasm with eosinophilia..     ///    This is the first report to describe the FOXP1-PDGFRA fusion gene in MPN.     ///    Comparing genomic DNA with mRNA sequences provides the possibility that the splicing process near the breakpoint junction in the FOXP1-PDGFRA fusion gene may use the normal splice donor site for intron 23a of FOXP1 and the cryptic splice acceptor site in exon 12 of PDGFRA. 