In this study, the partial structure of a CDKI gene, p27/Kip1, was determined.     ///    The p27/Kip1 and p21 CDKIs belong to the other group.     ///    "The latter group of the CDKIs, including p27/Kip1 and p21, are rarely mutated in human malignancies.. "    ///    The coding region of the p27/Kip1 gene consists of at least two exons and an intron of about 600 bp.     ///    "In addition, a large number of human cancers (432 cases) and cancer cell lines (20 lines) were analyzed for alterations of the p27/Kip1 gene by Southern blot analysis and PCR/single-strand conformation polymorphism. "    ///    Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies..     ///    "In summary, no abnormalities of the p27/Kip1 gene were detected in human malignancies. "