To examine the function of such fusion genes, an expression plasmid containing the TMPRSS2:ERG (T1/E5) sequence (??RG) from a patient sample was constructed and transiently transfected into DU145 cells, which do not express the fusion gene.     ///    "By contrast, VCaP cells, which do contain TMPRSS2:ERG, were sensitized to cisplatin??nduced apoptosis through siRNA inhibition of the fusion gene. "