To determine whether acquisition of this chromosomal translocation is involved in the pathogenesis of LCT in CTCL, we examined 12 tumor samples from 9 CTCL patients, including 8 with LCT-CTCL and one with concurrent CTCL and Hodgkin's disease, for the presence of the t(2;5) translocation.     ///    Numerous CD30+ large cells were present in 4 LCT-CTCL consistent with secondary CD30+ ALCL. 