FIG-ROS) fusion gene dramatically accelerates ICC development and that its inactivation in established tumors has a potent antitumor effect.     ///    "Specifically, we showed that the fused-in-glioblastoma-c-ros-oncogene1 (FIG-ROS1(S). "    ///    Mouse model of intrahepatic cholangiocarcinoma validates FIG-ROS as a potent fusion oncogene and therapeutic target.. 