In the pediatric solid tumor alveolar rhabdomyosarcoma, a consistent t(2;13)(q35;q14) or variant t(1;13)(p36;q14) translocation generates PAX3-FKHR or PAX7-FKHR fusion proteins, respectively.     ///    "In contrast, PAX7-FKHR overexpression results from fusion gene amplification. "    ///    "Thus, gene-specific mechanisms were selected to overexpress PAX3-FKHR and PAX7-FKHR in alveolar rhabdomyosarcoma, presumably due to differences in regulation between the wild-type loci. "    ///    "Furthermore, PAX3-FKHR and PAX7-FKHR overexpression occurs by distinct mechanisms. "