The implication of the caveolin genes, CAV1/CAV2, as a common genetic factor influencing both IOP variations and POAG may provide new insights of the underlying mechanism leading to glaucoma and glaucomatous visual field loss..     ///    "We successfully replicated the associations with GAS7 (P = 7.4 ?? 10(-3)) for IOP, and also identified a previously reported POAG locus in the CAV1/CAV2 region to be associated with IOP (P = 3.3 ?? 10(-3)). "    ///    Exome array analysis identifies CAV1/CAV2 as a susceptibility locus for intraocular pressure.. 