Dual FRAP studies revealed that CBFbeta colocalized with AML1-ETO within the nucleus, resulting in reduced mobility of CBFbeta.     ///    "Using gel-shift assay, we showed that AML1-ETO and AML1-MTG16 bound to a series of AML1 consensus DNA-binding sites with different affinities. "    ///    The dimerization domain (nervy homology region 2) of ETO is responsible for the reduced mobility of AML1-ETO. 